Omnix Medical tested its novel antimicrobial peptide, OMN51, on clinical isolates of multi-drug-resistant Pseudomon as aeruginosa collected from cystic fibrosis patients, in collaboration with Beilinson – Rabin Medical Center.
The results demonstrated rapid bactericidal activity with complete clearance within 1-8 hours and minimal cytotoxicity to human cells.
OMN51 represents a first-in-class, membrane-targeting therapeutic showing promise against MDR P. aeruginosa.
Authors: Moshe Heching, Moshe Cohen-Kutner, Haim Ben-Zvi, Liora Slomianksy, Elital Chass Maurice, Noa Nur Maymon, Shira Mandel, Michal Oholy, Rony Moses, Michal Lavon, Katherine Kaufman, Orel Mayost Lev-Ari,Tamar Shachar, Joel Weinberg, Mordechai R. Kramer and Niv Bachnoff.